Dhirubhai Mehta married Nandini, daughter of veteran Gandhian and freedom fighter Shri. Radhakrishna Bajaj, who has devoted his entire life in the field of constructive work which includes khadi, welfare of women, rural development, Sarvodaya and Go -Seva. She has stood as the main support for all the ventures, adventures and activities done by Dhirubhai.
Dhirubhai’s wife Nandini Mehta worked as a lecturer. She is also a reputed Hindi Poetess. They have a son Nirad and daughter in law Vaishali Hodarkar -both Chartered Accountants and now settled in Singapore. His daughter Maitry is married to Mr. Devang Shah and both are Chartered Accountants by profession. Dhirubhai has three grand children viz Tara Mehta, Kanika Shah and Aman Shah.